goal 55 - 10 Cardiovascular Disease and Risk Management terkhususnya PDF Lipid Management in Diabetes The 2019 European Society of CardiologyEuropean Atherosclerosis Society Dyslipidemia Guidelines go further and recommend an LDLC goal of 55 mgdL for patients with very highrisk ASCVD and to consider an even lower goal of 40 mgdL for patients with multiple cardiovascular events within 2 years despite optimal statin therapy 2 The advent Cardiovascular Benefit of Lowering LowDensity Lipoprotein Cholesterol 1026 For people with diabetes and atherosclerotic cardiovascular disease treatment with highintensity statin therapy is recommended to target an LDL cholesterol reduction of 50 from baseline and an LDL cholesterol goal of 55 mgdL Addition of ezetimibe or a PCSK9 inhibitor with proven benefit in this population is recommended if this therapy especially in those 55 years of age For any patient if the CAC score is 100 Agatston units or 75th percentile statin therapy is indicated unless otherwise deferred by the outcome of clinicianpatient risk discussion 10 Assess adherence and percentage response to LDLClowering medications and lifestyle PDF Consensus Statement by The American Association of Clinical For very highrisk patients the goal is an LDLC of 14 mmolL 55 mgdL For moderaterisk patients in primary prevention the goal is LDLC 26 mmolL 100 mgdL The guideline task force presumably believed that having defined LDLC goals facilitates cholesterollowering therapy in clinical practice Additionally following the ESCEAS Guidelines for the Management of High Blood Cholesterol CHOLESTEROL CLINICAL PRACTICE GUIDELINES AHAASA Journals LDL goals For primary prevention 70 mgdL is recommended for adults aged 4075 It is reasonable to treat those aged 2039 with diabetes and other ASCVD risk factors For secondary prevention 55 mgdL Lipid panel should be obtained At time of diabetes diagnosis and annually At initiation and after 412 weeks of Evolving Management of LowDensity Lipoprotein Cholesterol A LDL cholesterol macan35 How low can you safely go Harvard Health A therapeutic regimen to reduce LDLC by 50 from baseline and to achieve LDLC goal of 70 mgdL 18 mmolL on nonstatin therapies are recommended if a target reduction of 50 in LDLC values from baseline and a treatment goal of 55 mgdL are not achieved 5 The 2022 ACC ECDP on the role of nonstatin therapies in ASCVD Lowdensity lipoprotein cholesterollowering therapy in the primary Recent studies have suggested that more aggressive goals for LDL levels in people who already have CVD can decrease risk even further Lowering LDL cholesterol has been shown to lower risk of cardiovascular disease Recent studies have suggested that more aggressive goals for LDL levels in people who already have CVD can decrease 2022 ACC Expert Consensus Decision Pathway on the Role of Nonstatin The goal was to provide practical guidance for clinicians and patients in situations not covered by the 2018 AHAACCmultisociety cholesterol guideline until such time as the next round of guidelines can formally review recent scientific evidence and cardiovascular outcomes trials of newer agents for ASCVD risk reduction are completed Rationale for our approach and treatment goals Our recommendations for statin therapy are based upon the LDLC level and baseline CVD risk as discussed in the sections that follow algorithm 1 Our goal is to reduce CVD events via LDLC lowering A shared decisionmaking approach is very important in particular in those at intermediate achieve a goal lowdensity lipoprotein cholesterol LDLC of 55 mgdL and those at very high ASCVD risk should be treated to achieve LDLC 70 mgdL Treatment for moderate and high ASCVD risk patients may begin with a moderateintensity statin to achieve an LDLC 100 mg dL while the LDLC goal is 130 mgdL for otan4d login those at low risk
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